SCREENING OF ANTIBACTERIAL, CYTOTOXIC AND PESTICIDAL ACTIVITIES OF ABROMA AUGUSTUM (L.) SEEDS EXTRACT
SCREENING OF ANTIBACTERIAL, CYTOTOXIC AND PESTICIDAL ACTIVITIES OF ABROMA AUGUSTUM (L.) SEEDS EXTRACT
Homayra Binta Sujaye1, Md. Mehedi Hasan1, Mim Islam1, Biswanath Sikdar2,
Uzzal Kumar Acharjee1, Md Faruk Hasan2,*
1Department of Genetic Engineering and Biotechnology, University of Rajshahi, Rajshahi
6205, Bangladesh.
2Department of Microbiology, University of Rajshahi, Rajshahi 6205, Bangladesh.
*Corresponding Author Email: faruk_geb@ru.ac.bd
| A R T I C L E I N F O
Article Type: Research Received: 23, July. 2023. Accepted: 27, August. 2023. Published: 30, August. 2023.
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A B S T R A C T
Abroma augustum is an important medicinal plant in Bangladesh, rightly called as Ulatkambal in Bengali and Devil’s cotton in English. Present study was done to assess the antibacterial, toxicity, and pesticidal activities of A. augustum seeds extract. The antibacterial activity of A. augustum was evaluated using disc diffusion method against some pathogenic bacteria. Serial dilution technique was used to determine the potency of antibacterial activity. Minimum inhibitory concentration (MIC) of A. augustum was also studied against tested organisms. Toxicity of A. augustum was determined using brine shrimp lethality bioassay method. Pesticidal activity of A. augustum extract was tested towards Sitophilus oryzae adults. In case of antibacterial screening of A. augustum showed highest 27 mm diameter inhibition zone against Salmonella typhii at the concentration of 200µg/disc. Highest MIC value was found 250 mg/ml while the lowest MIC value was found 100 mg/ml in the selected bacteria. In toxicity activity test, LC50 (lethal concentration, 50%) of the extract against brine shrimp nauplii was 150µg/ml after 12h hour. In pesticidal activity, highest mortality and repellency was 70.33% and 60.3%, respectively towards S. oryzae adults. From the above results it can be concluded that the plant extract has moderate antibacterial activity against the tested bacteria, moderate toxicity and high pesticidal activity. The findings of the present research may be helpful for identify biological agents and drug designing for antibacterial activity. |
| Keywords:
Abroma augustum, Seeds extract, Antibacterial activity, Toxicity, Pesticidal activities
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